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Large scale production of mRNA vaccines consists in a 1 or 2-step in vitro reaction followed by a purification platform with multiple steps that can include Dnase digestion precipitation chromatography or tangential flow filtration. Learn More About the Acquisition.


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. In this review we describe the current state-of-art of mRNA vaccines focusing on the challenges and bottlenecks of manufacturing. Fully encapsulated in single-use modules the membranes used in the hollow fiber filter modules from Repligen are constructed using four chemistries that are anisotropic in structure to deliver high flux rates excellent separation and low protein binding for higher product yields. This Product is Now Part of Sartorius Portfolio.

This website uses cookies to help provide you with the best possible online experience. The Sartoflow 150 Auto TMP control is a single-use tangential flow filtration SUTFF semi-automated system designed for pilot or small-scale process ultrafiltration and diafiltration UFDF applications at 2-20 L batch volumes. System utilizes ⅜ in.


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